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Efficient sample pooling strategies for COVID-19 data gathering

Szapudi, I.

2020-04-07 epidemiology
10.1101/2020.04.05.20054445 medRxiv
Show abstract

Sample pooling of CoViD-19 PCR tests has been recently proposed as a low cost alternative to individual tests. We show that sample pooling is efficient as long as the fraction of the population infected is relatively small. Fisher information theory suggests a rule of thumb that for low infection rates p, pooling 2/p samples is close to optimal. We present a simple strategy for survey design when not even a ballpark estimate of the infection rate is available.

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