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A statistical method of batch screening entrying population from abroad by stages and groups in COVID-19 nucleic acid testing

Yuan yuan, C.

2020-04-07 epidemiology
10.1101/2020.04.02.20050914 medRxiv
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PurposeTo screen for COVID-19 patients in immigration using minimal nucleic acid testing (NAT). MethodsIn the first phase, nasopharyngeal swab samples from the inbound population were numbered and grouped. The samples in the group were mixed together, and a NAT test was performed. When the test result is negative, it means that everyone in the group is not infected and the screening of the group is complete. When the test results were positive, the group moved on to the second stage. In the second stage, all samples in the positive group will be tested individually for NAT. ResultsThe advantages and considerations of the method are discussed. Prevalence in the incoming population was a determinant of the sample size within the group. The lower the incidence, the larger the sample size within the group, the higher the savings in NAT and testing costs. ConclusionThis method has significant efficiency and cost advantages in COVID-19 screening. It can also be used to screen other populations, such as community populations and people at high risk of infection, etc.

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