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Algorithm for theoretical mapping of bio-strings for co-expression: bridging genotype to phenotype

Prakash, O.

2020-03-06 bioinformatics
10.1101/2020.03.05.979781 bioRxiv
Show abstract

Identification of possibility of co-expression or co-performance directly from set of bio-strings as protein sequences represents an important problem of bridging between genotype to phenotype. This algorithm presents above bridging. Algorithm was implemented with proteins known from human hormone signaling system. Co-expression of proteins was cross-validated through human gene COXPRESdb v7 database. Possibility of protein-protein interaction (PPI) was also cross checked through STRING database. Results were found to be effectively fascinating. Considering the indications from results, this algorithm can be adopted for theoretical identification of co-expression or co-performance of bio-strings.

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