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Application of the Adaptive Validation Design to estimate the association between transmasculine/transfeminine status and self-inflicted injury among transgender and gender-nonconforming children and adolescents.
2020-02-23
epidemiology
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AO_SCPLOWBSTRACTC_SCPLOWO_ST_ABSBackgroundC_ST_ABSAn internal validation substudy compares an imperfect measurement of a variable with a gold standard measurement in a subset of the study population. Validation data permit calculation of a bias-adjusted estimate, expected to equal the association that would have been observed had the gold standard measurement been available for the entire study population. Guidance on optimal sampling of participants to include in validation substudies has not c...
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