Back

Midbrain modulation of conditioned learning

Tan, K. R.; Rizzi, G.; Li, Z.; Hogrefe, N.

2020-02-07 neuroscience
10.1101/2020.02.07.936963 bioRxiv
Show abstract

The firing activity of striatal cholinergic interneurons (CINs) is a neural correlate of conditioned learning. However, its circuitry is not entirely described. Here we report that midbrain GABA and Glutamate neurons discriminate auditory cues and encode the association of a predictive stimulus with a footshock. Through their mono- and di-synaptic inputs via the thalamic-parafasicular sub-nucleus onto CINs, they contribute to processing fear learning.

Matching journals

The top 6 journals account for 50% of the predicted probability mass.

1
eLife
● 5828 papers in training set
Top 5%
15.0%
Similar papers in this journal
2
The Journal of Neuroscience
● 1025 papers in training set
Top 1%
11.8%
Similar papers in this journal
3
eneuro
● 439 papers in training set
Top 0.3%
9.6%
Similar papers in this journal
4
Nature Communications
○ 5641 papers in training set
Top 21%
7.8%
Similar papers in this journal
5
Current Biology
○ 665 papers in training set
Top 3%
4.3%
Similar papers in this journal
6
Cerebral Cortex
◐ 396 papers in training set
Top 2%
3.2%
50% of probability mass above
7
Journal of Neuroscience Methods
○ 122 papers in training set
Top 0.7%
2.8%
8
Scientific Reports
○ 3612 papers in training set
Top 38%
2.6%
9
Cell Reports
○ 1498 papers in training set
Top 15%
2.4%
10
European Journal of Neuroscience
○ 189 papers in training set
Top 1%
2.4%
11
Frontiers in Cellular Neuroscience
○ 91 papers in training set
Top 0.7%
2.4%
12
Frontiers in Neuroscience
○ 256 papers in training set
Top 3%
1.7%
13
PLOS Biology
● 486 papers in training set
Top 4%
1.7%
14
Frontiers in Neural Circuits
○ 43 papers in training set
Top 0.3%
1.7%
15
Science Advances
● 1243 papers in training set
Top 21%
1.7%
16
Brain
◐ 168 papers in training set
Top 2%
1.5%
17
Communications Biology
○ 993 papers in training set
Top 18%
1.4%
18
Proceedings of the National Academy of Sciences
● 2444 papers in training set
Top 31%
1.4%
19
Neuropsychopharmacology
○ 153 papers in training set
Top 2%
1.3%
20
Cell Reports Methods
○ 165 papers in training set
Top 3%
1.1%
21
Current Research in Neurobiology
○ 16 papers in training set
Top 0.1%
1.1%
22
PLOS ONE
● 5266 papers in training set
Top 57%
0.9%
23
Neuron
○ 337 papers in training set
Top 5%
0.8%
24
Frontiers in Behavioral Neuroscience
○ 49 papers in training set
Top 0.9%
0.8%
25
Nature Neuroscience
○ 252 papers in training set
Top 5%
0.8%
26
iScience
○ 1154 papers in training set
Top 36%
0.8%
27
Learning & Memory
● 23 papers in training set
Top 0.3%
0.6%

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.