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Magnetic Resonance Imaging Simulation of the Skull Base, Oral Cavity, Pharynx, and Larynx: Advanced Imaging Protocol for a Radiation Oncology Center

West, N. A.; McCullum, L.; Cheruvelil, J. T.; Dinh, V. T.; Ding, Y.; Wang, J.; Shah, K.; Learned, K.; Chen, M.; Phan, J.; Lee, A.; Garden, A.; Rosenthal, D.; Fuller, C. D.

2026-10-07 radiology and imaging
10.64898/2026.10.05.26364781 medRxiv
Show abstract

Head and neck radiation oncology, with its complex locality and epidemiology, requires various imaging techniques to achieve sufficient visualization. Through collaboration with medical physicists, radiation therapists, radiation oncologists, and neuroradiologists, our group clinically implemented a standard set of magnetic resonance imaging (MRI) sequences on an MR-simulation scanner for three anatomical regions: skull base, oral cavity, and larynx/pharynx. A total of 41 patients with head and neck cancer and 3 volunteers were scanned on either a 1.5T or 3T MR-simulation scanner. Sequences described include Dixon-based approaches, SPAIR-based approaches, short T2-based approaches, and quantitative imaging methods. We describe and outline the steps to optimize these notable MRI sequences to aid in successful implementation in a radiation oncology clinic.

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