Electrical Stunning does not affect Brain Tissue Integrity and Stress Response in Larval Zebrafish
Burkhardt, D.-S.; Schultz, K.; Glaser, M.; Krais, S.; Maile, D.; Koehler, H.-R.; Triebskorn, R.; Arrenberg, A. B.
Show abstract
Electrical stunning is a humane euthanasia method for larval zebrafish, and a suitable euthanasia protocol has recently been established. Here, we assess the associated stress response and tissue integrity. When compared to MS-222 overdose and hypothermia, electrical stunning caused no significant Hsp70 increase. Brain tissue was preserved and muscle tissue affected only slightly. Our results support the suitability of electrical stunning for humane euthanasia and artifact-free post-mortem analyses.
Matching journals
The top 5 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- An optimized method for high-quality RNA extraction from distinctive intrinsic laryngeal muscles in the rat model. 92%
- Ultrasonic rewarming of cryopreserved alginate encapsulated liver spheroids 92%
- Organophosphorus diisopropylfluorophosphate (DFP) intoxication in zebrafish larvae causes behavioral defects, neuronal hyperexcitation and neuronal death 91%
Similar papers in this journal
- Consecutive treatments of methamphetamine promote the 4 development of cardiac pathological symptoms in zebrafish 93%
- An amino-terminal fragment of apolipoprotein E4 leads to behavioral deficits, increased PHF-1 immunoreactivity, and mortality in zebrafish 92%
- Repeated exposure to nanosecond high power pulsed microwaves increases cancer incidence in rat 91%
Similar papers in this journal
- Effects of head-only exposure to 900 MHz GSM electromagnetic fields in rats : changes in neuronal activity as revealed by c-Fos imaging without concomitant cognitive impairments 91%
- Breathome discriminate Ischemic Heart Disease 90%
- Neutralizing effects of small molecule inhibitors and metal chelators on coagulopathic Viperinae snake venom toxins 89%
Similar papers in this journal
- Overnight caloric restriction prior to cardiac arrest and resuscitation leads to improved survival and neurological outcome in a rodent model 90%
- Systematic review protocol: Quantitative susceptibility mapping of brain iron accumulation in neurodegenerative diseases. 89%
- Rapid and efficient optical tissue clearing for volumetric imaging of the intact and injured spinal cord in mice 89%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.