Back

Simple Electroporation of Chlamydomonas reinhardtii Strains with an Intact Cell Wall

Messmer, M.; de Carpentier, F.; Lam, E.; Hong, M.; Wakao, S.; Schroda, M.; Niyogi, K. K.

2026-05-05 molecular biology
10.64898/2026.04.30.721989 bioRxiv
Show abstract

Chlamydomonas reinhardtii is a model green alga extensively used to study photosynthesis and cilia using molecular biology and genetics. Electroporation is a very common technique to transform DNA into the nuclear genome, which is essential to generate mutant collections and express transgenes. Here, we describe a simple, fast, and efficient protocol to transform strains with an intact cell wall. It achieves a good transformation efficiency without cell wall digestion or use of commercial kits and is compatible with the widely available Gene Pulser electroporation system. Key featuresO_LIHigh transformation efficiency of Chlamydomonas reinhardtii strains with an intact cell wall. C_LIO_LIFaster than currently available electroporation protocols. C_LI

Matching journals

The top 6 journals account for 50% of the predicted probability mass.

1
PLOS ONE
4510 papers in training set
Top 7%
22.6%
2
Plant Methods
39 papers in training set
Top 0.1%
12.4%
3
Frontiers in Plant Science
240 papers in training set
Top 2%
4.9%
4
Scientific Reports
3102 papers in training set
Top 27%
4.3%
5
The Plant Journal
197 papers in training set
Top 1%
3.6%
6
ACS Synthetic Biology
256 papers in training set
Top 1.0%
3.6%
50% of probability mass above
7
Frontiers in Bioengineering and Biotechnology
88 papers in training set
Top 0.6%
3.6%
8
Algal Research
20 papers in training set
Top 0.1%
3.6%
9
Current Protocols
13 papers in training set
Top 0.1%
3.3%
10
Plants
39 papers in training set
Top 0.7%
2.4%
11
Microorganisms
101 papers in training set
Top 0.7%
1.7%
12
Journal of Bioinformatics and Systems Biology
14 papers in training set
Top 0.3%
1.1%
13
Bioinformatics
1061 papers in training set
Top 8%
1.0%
14
Plant Science
25 papers in training set
Top 0.9%
0.8%
15
BMC Genomics
328 papers in training set
Top 5%
0.8%
16
BMC Bioinformatics
383 papers in training set
Top 6%
0.8%
17
HardwareX
16 papers in training set
Top 0.3%
0.7%
18
Journal of Visualized Experiments
30 papers in training set
Top 0.8%
0.7%
19
International Journal of Molecular Sciences
453 papers in training set
Top 15%
0.7%
20
PeerJ
261 papers in training set
Top 15%
0.7%
21
Development, Growth & Differentiation
12 papers in training set
Top 0.1%
0.7%
22
Biology Methods and Protocols
53 papers in training set
Top 3%
0.7%
23
Plant Direct
81 papers in training set
Top 2%
0.7%
24
Plant Reproduction
12 papers in training set
Top 0.2%
0.6%
25
Talanta
12 papers in training set
Top 0.9%
0.6%
26
Journal of Microbiological Methods
11 papers in training set
Top 0.6%
0.6%
27
Applications in Plant Sciences
21 papers in training set
Top 0.4%
0.6%
28
G3 Genes|Genomes|Genetics
351 papers in training set
Top 3%
0.6%