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BioEngine: scalable execution and adaptation of bioimage AI through agent-readable interfaces

Mechtel, N.; Källander, H. D.; Cheng, S.; Zhang, H.; AI4Life Horizon Europe Program Consortium, ; Ouyang, W.

2026-04-22 bioinformatics
10.64898/2026.04.19.719496 bioRxiv
Show abstract

Foundation models and curated repositories have transformed bioimage AI, yet most biologists cannot readily run, adapt, or extend them on available hardware. BioEngine lls this gap as the execution and adaptation layer between curated AI and scalable compute, deployable on a laptop, workstation, or cluster. Scientists then screen models, ne-tune from the browser, enable real-time smart microscopy, and deploy analysis applications, all by describing their goal to an AI agent.

Matching journals

The top 1 journal accounts for 50% of the predicted probability mass.

50% of probability mass above

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.