Back

Seroprevalence of syphilis among sex workers in Nairobi, Kenya: a retrospective study

Loeb, K.; van Wyk, A.; Milner, K.; Lemaille, C.; Frederick, C.; Hunter, M.; Martens, B.; Lajoie, J.; Placide, M.; Rimoin, A. W.; Hoff, N. A.; Noyce, R.; Fowke, K. R.; Kimani, J.; Mckinnon, L.; Shaw, S. Y.; Stein, D. R.; Kindrachuk, J.

2026-03-24 infectious diseases
10.64898/2026.03.22.26349033 medRxiv
Show abstract

Syphilis is a sexually transmitted and bloodborne infection caused by Treponema pallidum spp. pallidum. Given the paucity of data on syphilis in Kenyan sex workers and gay, bisexual, and other men who have sex with men (GBMSM), we conducted a retrospective study of syphilis seropositivity in female sex workers (FSW) and GBMSM in Nairobi, Kenya. Seropositivity testing of cryopreserved plasma samples showed that 11.1% (72/647) were positive. Syphilis seropositivity was associated with HIV status, and FSWs were disproportionately represented in the seropositive group (66/72, 92%). Here, we report a higher seropositive rate than in previous studies in Kenya, and ongoing community and surveillance supports are important for addressing the ongoing public health impacts of syphilis.

Matching journals

The top 6 journals account for 50% of the predicted probability mass.

1
Sexually Transmitted Infections
21 papers in training set
Top 0.1%
17.1%
2
PLOS Neglected Tropical Diseases
378 papers in training set
Top 0.9%
12.2%
3
The Journal of Infectious Diseases
182 papers in training set
Top 0.5%
6.2%
4
PLOS ONE
4510 papers in training set
Top 29%
6.2%
5
Emerging Infectious Diseases
103 papers in training set
Top 0.3%
6.2%
6
The American Journal of Tropical Medicine and Hygiene
60 papers in training set
Top 0.7%
6.2%
50% of probability mass above
7
Clinical Infectious Diseases
231 papers in training set
Top 1%
4.7%
8
Journal of Clinical Microbiology
120 papers in training set
Top 0.5%
3.9%
9
PLOS Global Public Health
293 papers in training set
Top 2%
3.5%
10
Frontiers in Cellular and Infection Microbiology
98 papers in training set
Top 2%
3.0%
11
Scientific Reports
3102 papers in training set
Top 45%
2.7%
12
Tropical Medicine and Infectious Disease
12 papers in training set
Top 0.1%
2.0%
13
Open Forum Infectious Diseases
134 papers in training set
Top 0.9%
2.0%
14
BMC Infectious Diseases
118 papers in training set
Top 2%
1.8%
15
Transactions of The Royal Society of Tropical Medicine and Hygiene
16 papers in training set
Top 0.3%
1.5%
16
Journal of Infection
71 papers in training set
Top 2%
1.3%
17
Tropical Medicine & International Health
15 papers in training set
Top 0.4%
1.2%
18
Microbiology Spectrum
435 papers in training set
Top 5%
0.8%
19
The Lancet Microbe
43 papers in training set
Top 1%
0.8%
20
Antimicrobial Agents and Chemotherapy
167 papers in training set
Top 2%
0.7%
21
BMJ Open
554 papers in training set
Top 13%
0.7%
22
Frontiers in Medicine
113 papers in training set
Top 7%
0.7%
23
Frontiers in Microbiology
375 papers in training set
Top 10%
0.7%
24
mBio
750 papers in training set
Top 12%
0.7%
25
International Journal of Infectious Diseases
126 papers in training set
Top 4%
0.6%