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Cardiovascular Risk Factors Identified Among Homeless Adults in San Francisco: Recommendations for Evidence-Based Outreach Services From a Quality Improvement Initiative

Valliant, S. J.; Rodriguez, I.; Lee, A.; Kulik, C.; Punzalan, R.; Holbrook, L.; Tamayo, R.; Mendoza, R.; Puig, M.; Anderson, T.; Modan, Y.; Athwal, S.; Lugo, I.; Hernandez, M.; Silva-Castro, D.-E.; Petrides, M.; Alvarado, N.; Tang, K.

2026-03-24 public and global health
10.64898/2026.03.22.26349032 medRxiv
Show abstract

Objective: This preliminary public health report assessed acute and chronic health burdens, focusing on cardiovascular health, among unsheltered individuals experiencing homelessness. It aims to guide medical referrals, deliver targeted health education, and prioritize services within a community based nonprofit. Methods: A field based needs assessment used a structured questionnaire to evaluate acute and chronic health burdens. Clinical measures included blood pressure (BP), heart rate (HR), pain scores (normalized to 0 to 10), nicotine use, and diabetes prevalence. Of 72 initial responses, 59 BP, 65 HR, and 66 pain scores were usable. BP was classified per ACC/AHA (2017) guidelines [1], including Hypertensive Crisis. Nicotine and diabetes data from a secondary survey yielded 39 and 38 usable responses of 116. Ethical oversight ensured informed consent, participant capacity assessment, and emergency protocols. Data were analyzed descriptively. Results: Participants were predominantly male (N = 53 of 72) with ages ranging from 24 to 70 years (Mean = 42.96; Median = 41; N = 70). The cohort was primarily White/Caucasian (N = 30) and Black/African American (N = 27). Cardiovascular assessments revealed substantial acute risk: 72.88% (N = 43 of 59) of BP readings were classified as Total High Blood Pressure, and 10.17% (N = 6 of 59) met criteria for Hypertensive Crisis or higher, including readings of 210/137 mmHg and 286/127 mmHg. Mean and median HR were both 96 bpm (N = 65). Chronic symptom burden was notable, with a mean pain score of 3.74 and 19.70% (N = 13) reported severe pain (7 to 10). Self-reported comorbidities included current smoking in 15.38% (N = 6 of 39) and a history of diabetes in 13.16% (N = 5 of 38). Conclusion: Findings show a high prevalence of acute cardiovascular risk, particularly severe hypertension, among the unsheltered population. These results highlight the urgent need for improved outreach, targeted cardiovascular and primary care referrals, and follow up screenings. Expanding health education on the effects of uncontrolled diabetes and smoking is recommended to reduce future cardiovascular events.

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