Back

Association between Gestational Weight Gain on Obstetric-Perinatal Outcomes Among Women With Pre-pregnancy Overweight or Obesity in a Peruvian Public Hospital

Hernandez-Concepcion, F. C.; Pena-Cano, A.; Davila-Quispealaya, J. E.; Manrique-Franco, K.; Yanac-Telleria, W. M.; Yovera-Aldana, M.

2026-03-14 obstetrics and gynecology
10.64898/2026.03.12.26348271 medRxiv
Show abstract

ObjectiveTo evaluate the association between excessive gestational weight gain (GWG) and obstetric and perinatal outcomes among women with pre-pregnancy excess weight attending a public hospital in Lima, Peru. MethodsWe conducted a retrospective cohort study using routinely collected institutional records from Hospital Maria Auxiliadora. Women with singleton pregnancies and pre-pregnancy body mass index (BMI) [≥]25 kg/m{superscript 2} who delivered between January 2024 and August 2025 were included. Excessive versus non-excessive GWG was defined according to national guidelines. The primary outcome was a composite obstetric-perinatal outcome. Crude and adjusted relative risks (RRs) were estimated using Poisson regression with robust variance. Effect modification by pre-pregnancy BMI and maternal short stature was evaluated. ResultsOf 6082 records, 3118 met the eligibility criteria; 31.0% had excessive GWG. In adjusted analyses, excessive GWG was associated with a small increase in the risk of the composite outcome (aRR = 1.05; 95% CI: 1.01-1.09), but not with overall obstetric outcomes (aRR = 1.04; 95% CI: 0.99-1.09) or overall perinatal outcomes (aRR = 0.99; 95% CI: 0.85-1.15). The association varied according to pre-pregnancy BMI, with higher relative risks observed among women with obesity (classes I-III). ConclusionsAmong women with pre-pregnancy excess weight, excessive gestational weight gain was associated with a small increase in the risk of composite obstetric-perinatal outcomes but not with obstetric or perinatal outcomes analysed separately. The magnitude of the association differed across BMI categories, with stronger associations in higher obesity classes. These findings emphasise the importance of pre-pregnancy nutritional status when interpreting the potential impact of gestational weight gain on pregnancy outcomes.

Matching journals

The top 3 journals account for 50% of the predicted probability mass.

1
PLOS ONE
4510 papers in training set
Top 7%
22.2%
2
Obesity
19 papers in training set
Top 0.1%
18.3%
3
BMC Pregnancy and Childbirth
20 papers in training set
Top 0.1%
12.1%
50% of probability mass above
4
PLOS Global Public Health
293 papers in training set
Top 1%
8.1%
5
PeerJ
261 papers in training set
Top 2%
3.9%
6
BMJ Open
554 papers in training set
Top 6%
3.5%
7
The Journal of Clinical Endocrinology & Metabolism
35 papers in training set
Top 0.4%
3.5%
8
Journal of Clinical Medicine
91 papers in training set
Top 2%
3.5%
9
PLOS Medicine
98 papers in training set
Top 1%
3.5%
10
Scientific Reports
3102 papers in training set
Top 44%
2.7%
11
Cureus
67 papers in training set
Top 4%
0.9%
12
BMC Medicine
163 papers in training set
Top 6%
0.8%
13
JAMA Network Open
127 papers in training set
Top 4%
0.8%
14
Frontiers in Public Health
140 papers in training set
Top 8%
0.8%
15
Placenta
18 papers in training set
Top 0.2%
0.8%
16
European Journal of Public Health
20 papers in training set
Top 1.0%
0.8%
17
Frontiers in Pediatrics
29 papers in training set
Top 1.0%
0.7%
18
Public Health Nutrition
14 papers in training set
Top 0.6%
0.7%
19
International Journal of Obesity
25 papers in training set
Top 0.6%
0.7%
20
Clinical Infectious Diseases
231 papers in training set
Top 5%
0.7%
21
Frontiers in Endocrinology
53 papers in training set
Top 3%
0.6%
22
BMC Health Services Research
42 papers in training set
Top 2%
0.6%
23
BMC Public Health
147 papers in training set
Top 6%
0.6%