CarpeDiem, a per-day clinical parameters and pneumonia adjudication dataset for critically ill patients with suspected pneumonia
Gao, C. A.; Markov, N. S.; Kang, M.; Rasmussen, L. V.; Liao, W.-T.; Pawlowski, A.; Nannapaneni, P.; Guggilla, V.; Donnelly, H. K.; Clepp, R. K.; Pickens, C. O.; Nadig, N. R.; Stoeger, T.; Schneider, D.; Starren, J.; Walunas, T.; Wunderink, R. G.; Budinger, G. S.; Misharin, A. V.; Singer, B. D.; The NU SCRIPT Study Investigators,
Show abstract
Many analyses of critically ill patients focus on admission features and discharge outcomes, overlooking daily events and intercurrent complications. Pneumonia is a syndromic entity that is difficult to adjudicate outcomes without clinical expertise. Here, we examine clinical features on a day-by-day basis, mirroring the practice of daily multidisciplinary rounds, with annotated pneumonia episodes and outcomes. The Successful Clinical Response in Pneumonia Therapy (SCRIPT) CarpeDiem Dataset includes 21,931 patient-hospital-days from 704 patients enrolled in the SCRIPT study between June 2018 and May 2023. These patients were all receiving mechanical ventilation and underwent bronchoalveolar lavage to diagnose and establish the etiology of their pneumonia or an alternative diagnosis. The dataset captures patient demographics, daily clinical parameters, including vital signs, laboratory results, and mechanical support data, detailed pneumonia episode results adjudicated by critical care physicians, and outcomes. All data are de-identified per HIPAA Safe Harbor guidelines. This dataset offers a unique resource for analyzing the clinical trajectories of patients with severe pneumonia.
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