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Design and Rationale of the My Heart Counts Cardiovascular Health Study: a Large-Scale, Fully Digital Biobank, and Randomized Trial of Large Language Model-Driven Coaching of Physical Activity

2026-03-03 cardiovascular medicine Title + abstract only
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BackgroundCardiovascular disease remains the leading cause of global morbidity and mortality. The original My Heart Counts smartphone application demonstrated the feasibility of large-scale, fully digital recruitment and trial conduct, but was limited by platform exclusivity and the need for human experts to create text-based behavioral interventions. MethodsThe next-generation My Heart Counts smartphone application is a prospective, observational cohort study with an embedded randomized crosso...

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