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The Causal Impact of Natural Language Processing-Driven Clinical Decision Support on Sepsis Mortality in England: An Augmented Synthetic Control Analysis of NHS Trust-Level Data

2026-03-02 health informatics Title + abstract only
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BackgroundSepsis remains a leading cause of preventable hospital mortality in England, with NHS England reporting over 48,000 sepsis-related deaths annually. Natural language processing (NLP)-driven clinical decision support systems (CDSS) have been deployed in several NHS Trusts to enable automated early detection of sepsis from unstructured clinical notes, yet causal evidence of their effectiveness at the hospital level remains limited. ObjectiveTo estimate the causal effect of implementing N...

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