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Antithrombotic Therapy in Atrial Fibrillation Patients with Prior Complex Percutaneous Coronary Intervention: A Secondary Analysis of the Randomized ADAPT AF-DES Trial

2026-03-03 cardiovascular medicine Title + abstract only
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BackgroundIn patients with atrial fibrillation (AF) and stable coronary artery disease beyond 1 year after percutaneous coronary intervention (PCI), oral anticoagulant monotherapy is guideline-recommended; however, its efficacy and safety in patients with complex PCI remain uncertain. MethodsWe conducted a post-hoc analysis of the randomized ADAPT AF-DES trial comparing NOAC monotherapy versus NOAC plus clopidogrel in AF patients [≥]12 months after second- or third-generation drug-eluting st...

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