Clinical Evaluation of a Digital Biomarker for Joint Swelling in Inflammatory Arthritis based on Automated Quantification of Dorsal Finger Fold Patterns

2026-02-27 rheumatology Title + abstract only

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ObjectiveTo clinically evaluate a digital biomarker, the Finger Fold Index (FFI), derived from the ratio of joint diameter to finger fold surface area in hand photographs, for assessing joint swelling in inflammatory arthritis. MethodsSmartphone hand photographs from two routine care cohorts of patients with rheumatoid (RA) and psoriatic arthritis (PsA) were analyzed using a machine learning pipeline for automated detection and processing of proximal interphalangeal (PIP) joints. The FFI was cl...