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Multivariate brain-cognition covariance supports the criterion validity of cognitive screening performance

Sneidere, K.; Zdanovskis, N.; Litauniece, Z. A.; Usacka, A.; Gulbe, A. I.; Freibergs, Z.; Stepens, A.; Martinsone, K.

2026-02-28 psychiatry and clinical psychology
10.64898/2026.02.26.26347152 medRxiv
Show abstract

There is a predicted increase in older adults presenting with mild to severe cognitive impairment. Screening tools with high sensitivity are the first frontier in identifying a cognitive pathology; however, to ensure that they are measuring the intended concept or criterion, thorough psychometric procedures should be followed. In this study, convergent criterion validity of Riga Cognitive Screening Task was measured, using cortical thickness of regions of interest as the criterion. 106 older adults (Mage = 70.49, SD =8.08, 35.8% male) with varying levels of cognitive functioning were involved in the study. All participants underwent cognitive assessment with the screening task and a 3T MRI. Cortical thickness of selected temporal and parietal regions was used as a brain measure. Behavioural Partial Least Squares Correlation was conducted and one latent variable was extracted. The results confirmed that Riga Cognitive Screening Task shows good criterion validity, suggesting successful use for screening.

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