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Study protocol for microneurographic investigation of nociceptor sensitisation in Fibromyalgia Syndrome. (MICRO-FMS)
2026-02-26
pain medicine
Title + abstract only
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IntroductionChronic pain in fibromyalgia may be driven by abnormal ongoing activity in a subclass of C-fibre nociceptors known as Type1B or CMi nociceptors. As is common in C-nociceptor microneurography studies, the modest patient numbers in these prior studies generate large confidence intervals around the point estimate of the prevalence of this abnormal activity. This complicates the interpretation of the relative importance of this ongoing nociceptor activity as a pain generating mechanism i...
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