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Plasma Lipid Alterations Track Multidimensional Psychosis Severity Across Diagnostic Boundaries

2026-02-26 psychiatry and clinical psychology Title + abstract only
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BackgroundLipidomic alterations have been reported across schizophrenia (SCZ) and bipolar disorder (BD), but findings are heterogeneous and often overlap across diagnoses, limiting diagnostic specificity. Associations between lipid profiles and illness severity have also been inconsistent when assessed using single symptom scales, raising the possibility that unidimensional measures fail to capture biologically relevant variation. Whether plasma lipidomic alterations relate to multidimensional p...

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