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Clinical and genetic correlates of a circadian subtype of depression in the Australian Genetics of Depression Study

2026-02-25 psychiatry and clinical psychology Title + abstract only
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BackgroundWhile commonly accepted depressive subtypes reflect phenotypic differences, there has been minimal progress in identifying discrete pathophysiological pathways, biomarkers or differential therapeutic approaches which effectively guide clinical management. AimsTo test the biological validity and clinical utility of a circadian subtype of depression on the basis of clinical course, differential medication response (self-reported) and genetic risk profile. MethodsCross-sectional data we...

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