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Standardisation of terminology, calculation and reporting for assigning exposure duration to drug utilisation records from healthcare data sources: the CreateDoT framework

2026-02-19 epidemiology Title + abstract only
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BackgroundIn pharmacoepidemiological studies, days of treatment (DoT) duration associated with individual electronic drug utilization records (DUR) are usually missing. Researcher-defined duration (RDD) calculation approaches, as opposed to data-driven approaches, can be used to estimate DoT based on the specific choices and assumptions made by investigators. These are usually underreported or even undocumented. We aimed to develop a framework for the standardization of terminology, formulas, im...

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