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Gestational Environment Captured by the Neonatal Metabolome is not Predictive of Later Inflammatory Bowel Disease

2026-02-18 gastroenterology Title + abstract only
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BackgroundGestational exposures may contribute to the newborns lifetime risk of inflammatory bowel disease (IBD). While gestational influences are associated with IBD onset, the causality and confounding of such exposures are difficult to ascertain. The neonatal metabolome provides a metabolic snapshot of gestational influences. ObjectiveWe tested the neonatal metabolomes ability to predict future IBD, to assess whether gestational exposures are reflected in early molecular precursors of the di...

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