Integration of clinical and genomic data defines prognostic phenotypes in resected perihilar cholangiocarcinoma: a national multicenter study

2026-02-17 transplantation Title + abstract only

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Background & AimsPerihilar cholangiocarcinoma is an aggressive malignancy with clinical heterogeneity and poor long-term outcomes after resection. Current prognostic assessment relies mainly on anatomical staging and pathological features, which incompletely capture the entire postoperative risk. We aimed to determine whether integrative analysis of clinical, surgical, pathological and tumor genomic data could improve time-resolved, individualized recurrence-risk prediction after curative-intent...

Integration of clinical and genomic data defines prognostic phenotypes in resected perihilar cholangiocarcinoma: a national multicenter study

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