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Paediatric meningoencephalitis in the molecular diagnostic era: Epidemiological insights from 1,198 suspected cases in Germany between 2016 and 2024
2026-02-22
infectious diseases
Title + abstract only
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BackgroundThe epidemiology of suspected pediatric meningoencephalitis has shifted in the era of conjugate vaccines and multiplex PCR diagnostics, with viral pathogens now predominating over bacterial causes. Updated epidemiologic data are essential to adapt diagnostic and therapeutic algorithms to current clinical practice. MethodsThis retrospective single-center study included children and adolescents <18 years who underwent lumbar puncture with cerebrospinal fluid multiplex PCR for suspected ...
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