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A Definitive Tcrbeta1/ Tcrbeta2 Antibody Pair For Determining T-Cell Monotypia As A Surrogate For Clonality In Lymphoma Diagnosis In Formalin Fixed Paraffin Embedded Material
2026-02-17
pathology
Title + abstract only
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T-cell lymphomas are often histologically indistinguishable from benign T-cell infiltrates. Clonality testing is frequently required for diagnosis. It lacks the spatial context and is slow and expensive, relying on complex, multiplexed PCR reactions, interpreted by experienced scientists or pathologists. We previously published details of a pair of highly specific monoclonal antibodies against the two alternatively used, but very similar, T-cell receptor {beta} constant regions, TCR{beta}1 and T...
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