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HDL-bound microRNAs modulating cholesterol efflux and homeostasis and incidence of acute myocardial infarction: A population-based case-cohort study

2026-02-12 cardiovascular medicine Title + abstract only
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BackgroundHDL particles can carry microRNAs (miRNAs), capable of regulating gene expression connected to HDL functions. Despite links to some cardiovascular risk factors, miRNA association with incident acute myocardial infarction (AMI) remains unclear. ObjectivesOur aim was to elucidate the association between HDL-bound miRNAs (HDL-miRNAs) and incident AMI using a non-targeted approach in a population-based study. MethodsWe conducted a case-cohort study including 247 participants from the REG...

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