Efficacy and safety of newer antibiotics versus generic antibiotics for hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia: a systematic review and meta-analysis of randomized controlled trials

2026-02-12 infectious diseases Title + abstract only

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BackgroundHospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP), particularly those caused by multi-drug resistant organisms (MDROs), often require newer antibiotic treatment. The efficacy and safety of newer antibiotics compared to generic antibiotics in randomized controlled trials (RCTs) have not been evaluated before. MethodsIn this systematic review, we searched RCTs in the United States National Library of Medicine (PubMed), Cochrane Central Reg...

Efficacy and safety of newer antibiotics versus generic antibiotics for hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia: a systematic review and meta-analysis of randomized controlled trials

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