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Targeting Cortico-Striatal-Amygdalar Networks via Theta-Band Frontoparietal Synchronization in Opioid Use Disorder: A Randomized tACS-fMRI Trial
2026-02-11
addiction medicine
Title + abstract only
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BackgroundTheta-band oscillation is integral to fronto-parietal connectivity in the executive control network and its top-down regulation on subcortical areas. External frontoparietal synchronization using theta-frequency transcranial alternating current (tACS) is a technology to potentially engage this network. In this pre-registered, triple-blind, sham-controlled trial (NCT03907644), we tested this intervention targeting the right frontoparietal network in people with opioid use disorder (OUD)...
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