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Prognostic Impact of Embryonal and Yolk Sac Components in Metastatic Germ Cell Tumors. Insights from an International Cohort.

2026-02-12 oncology Title + abstract only
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PurposePrognosis in metastatic non-seminomatous germ cell tumors (mNSGCT) is currently guided by the IGCCCG classification, which incorporates tumor markers, organs involved with metastatic disease, and primary site but not histologic subtype. We aimed to evaluate whether specific histological components provide additional prognostic information in a large international mNSGCT cohort. Patient and MethodsWe analyzed clinical, pathologic, and outcome data from 662 patients with mNSGCT across mult...

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