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Developing and Testing an Engineering Framework for Curiosity-Driven and Humble AI in Clinical Decision Support

2026-02-07 health informatics Title + abstract only
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BackgroundWe present BODHI (Balanced, Open-minded, Diagnostic, Humble, and Inquisitive), an engineering framework for curiosity-driven and humble clinical decision support AI. Despite growing capabilities, large language models (LLMs) often express inappropriate confidence, conflating statistical pattern recognition with genuine medical understanding. BODHI addresses this through a dual-reflective architecture that: (1) decomposes epistemic uncertainty into task-specific dimensions, and (2) cons...

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