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Proteomic Biomarkers Differentiate Bacterial Infections in Febrile Infants: A Multicentre Prospective Study
2026-02-05
infectious diseases
Title + abstract only
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ObjectivesTo identify and validate plasma host-response protein biomarkers that improve discrimination of bacterial infection in febrile infants [≤]90 days of age, and to assess whether novel biomarkers add value beyond established markers. MethodsSub-study of the prospective multicentre Febrile Infant Diagnostic Assessment and Outcome (FIDO) cohort. Novel biomarkers were identified through plasma proteomic profiling (Olink(R)) and combined with biomarkers and signatures from the literature ...
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