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Impact of Triple-drug Mass Drug Administration on Prevalence of Antigen and Antibodies to Lymphatic Filariasis in Samoa, 2018-2019

2026-02-03 epidemiology Title + abstract only
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BackgroundIn 2018, Samoa was the first country to distribute nationwide triple-drug mass drug administration (MDA) for lymphatic filariasis (LF) elimination. Prevalence of filarial antigen (Ag) is the main programmatic indicator used to define elimination target thresholds; however, anti-filarial antibodies (Ab) may provide more sensitive measures of transmission compared Ag. We aimed to investigate the utility of Ag and Ab to measure the impact of one round of triple-drug MDA on LF transmission...

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