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Running therapy improves clinical symptoms and reorganizes dynamic brain networks in affective disorders.

2026-02-02 psychiatry and clinical psychology Title + abstract only
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BackgroundExercise therapy reduces depressive and anxiety symptoms, but its neural mechanisms are not fully understood. We examined whether and how running therapy reorganizes dynamic brain functional connectivity in affective disorders. MethodsAt baseline, resting-state fMRI was collected from 66 healthy controls and 50 individuals with affective disorders. Co-activation patterns analyses (CAPs) identified recurring whole-brain network states characterized by spatial patterns of regional co-ac...

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