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Multi-component Stroke Intervention and Long-term Biofunctional Outcomes: A Secondary Analyses of the SINEMA Trial

2026-01-30 geriatric medicine Title + abstract only
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BackgroundThe one-year SINEMA trial demonstrated improved blood pressure (BP) control and reduced mortality up to 72 months after the intervention. This article aims to assess between-arm differences in mean annual cumulative BP and to explore whether the associations between cumulative BP and biofunctional outcomes differed by trial arm. MethodsPost-hoc secondary analysis of the SINEMA cluster-randomized trial, which recruited 1299 adults with stroke from 50 rural villages in Hebei, China, bet...

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