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Shared and Distinct Neural Signatures of Cue-Induced Response in Substance and Behavioral Addictions: A Coordinate-Based Neuroimaging Meta-Analysis

2026-01-25 addiction medicine Title + abstract only
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As the global burden of addiction intensifies, the neurobiological commonalities and distinctions between substance use disorders (SUDs) and behavioral addictions (BAs) remain poorly characterized. This coordinate-based meta-analysis of 59 fMRI articles (n = 2,951) mapped the neural signatures of visual cue-reactivity across the addictive disorders. Our results revealed a universal core network shared by SUDs and BAs centered in the bilateral opercular inferior frontal gyrus, suggesting a shared...

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