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Serum S100A8/S100A9 is associated with increased risk of brain metastasis in patients with inflammatory breast cancer

2026-01-22 oncology Title + abstract only
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BackgroundInflammatory breast cancer (IBC) is a rare and highly aggressive form of breast cancer with an increased propensity to metastasize to distant organs including the brain. Higher serum levels of the calcium-binding proteins S100A8/A9, particularly of S100A9, have emerged as a clinically and biologically significant factor in aggressive breast cancers that are associated with poorer prognosis, tumor progression, and resistance to therapy. However, its contribution in IBC specifically rema...

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