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Unveiling the Porphyromonadaceae-TFF1 Interaction and ITGAM as Critical Factors in Post-operative Recurrence of Crohn's Disease

2026-01-19 gastroenterology Title + abstract only
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BackgroundCrohns disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract characterized by high post-operative recurrence (POR) rates, reaching up to 90% within one year. Current clinical and endoscopic predictors show limited accuracy. ObjectiveThis study aimed to identify molecular mechanisms associated with POR at the time of surgery through integrated transcriptomic and bacteriomic analyses of ileal tissue. DesignIleal samples were obtained during surgery from 20 patie...

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