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Protein-based genomic analysis for the identification of risk loci associated with acute respiratory distress syndrome
2026-01-16
genetic and genomic medicine
Title + abstract only
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BackgroundAcute respiratory distress syndrome (ARDS) is a life-threatening lung condition that requires admission to an intensive care unit (ICU). Sepsis is one of the leading causes of ARDS and understanding protein regulation during sepsis could reveal key mechanisms that predispose patients to ARDS. We performed genome-wide association studies (GWAS) on ARDS biomarkers levels to identify protein quantitative trait loci (pQTLs) and genes which could be associated with ARDS risk. MethodsGWAS w...
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