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Arousal network determines mean of systolic blood pressure and chemoreflex pathway determines dispersion of systolic blood pressure during N2 sleep in patients of moderate to severe obstructive sleep apnea
2026-01-13
respiratory medicine
Title + abstract only
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IntroductionObstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction during sleep, leading to intermittent hypoxia, sleep fragmentation, and autonomic dysregulation. These disturbances contribute to nocturnal blood pressure (BP) surges and increased cardiovascular risk. While sleep-stage-dependent BP modulation is well established, high-resolution data on sleep-stage- specific systolic BP variability (BPV) in OSA are limited. This study examined beat-to-beat systolic ...
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