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Early deviations from normative brain morphology and cortical microstructure in schizophrenia spectrum disorders

2026-01-11 psychiatry and clinical psychology Title + abstract only
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In schizophrenia spectrum disorders (SSD), structural alterations of the gray matter (GM) and white matter (WM) have been widely described. However, the complex interplay between early disease-related changes and ongoing brain maturation challenges our ability to identify early biomarkers. In this study, we investigated structural abnormalities and their association with symptoms in a drug-naive or minimally medicated sample comprising 113 patients with SSD and 112 neurotypical controls. Specifi...

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