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Bridging Genomics and Pharmacoepidemiology to Expand Treatment Options for Alcohol Use Disorder
2026-01-11
addiction medicine
Title + abstract only
View on medRxiv
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Alcohol use disorder (AUD) is a chronic, relapsing condition and a major public health problem. However, few medications are approved to treat AUD, and those available show limited efficacy. Drug repurposing is a cost-effective strategy to identify novel therapeutic uses for existing medications. Here, we describe a pipeline that integrates genetic and electronic health record (EHR) data to identify and evaluate drugs to be repurposed for treating AUD. Our approach comprises 1) alcohol-associate...
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