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Is psychomotor retardation associated with treatment response in adults with depression? A secondary analysis of nine randomised controlled trials.

2026-01-16 psychiatry and clinical psychology Title + abstract only
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BackgroundPsychomotor retardation is characterised by slowed motor and cognitive processes. Although associated with greater illness severity in depression, its relationship with treatment response is unclear. We examined whether psychomotor retardation is associated with treatment outcomes in depression. MethodsWe conducted a secondary analysis of individual participant data from nine randomised controlled trials of pharmacological, psychological and exercise-based treatments for unipolar depr...

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