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Personas Shift Clinical Action Thresholds in Large Language Models

2026-01-02 health informatics Title + abstract only
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Background and aimsClinical LLM deployment is shifting from feasibility to liability, while current guidance largely treats model behavior as a control problem. We tested whether decision-style system prompts shift clinical action thresholds when clinical facts are held constant, and whether these shifts are consistent across settings and models. MethodsWe defined nine physician personas by crossing three ethical orientations (duty-, care-, utilitarian) with three cognitive styles (intuitive, i...

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