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Initial development and pragmatic clinical validation of a static disease severity instrument for pyoderma gangrenosum: Investigator Global Assessment for PG (IGAPg).
2026-01-01
dermatology
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BackgroundPyoderma gangrenosum (PG) is a rare neutrophilic ulcerative dermatosis with no FDA-approved therapies and limited validated outcome measures. Investigators Global Assessments (IGAs) are widely used in dermatology but often lack objective criteria, robust validation, and comparability across studies. There remains a critical need for a PG-specific, standardized, and validated severity instrument. MethodsWe developed and conducted initial validation of the Investigator Global Assessment...
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