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Decreased within-default mode network connectivity with accelerated intermittent theta burst stimulation across unipolar and bipolar depression: Candidate transdiagnostic circuit marker for treatment response

2026-01-01 psychiatry and clinical psychology Title + abstract only
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BackgroundAn accelerated schedule of intermittent theta burst stimulation (aiTBS) has been shown to improve clinical efficacy of transcranial magnetic stimulation for bipolar disorder (BD) and major depressive disorder (MDD). We investigated the functional connectivity changes underpinning clinical effects of aiTBS on transdiagnostic treatment-resistant depression (TRD). MethodsData were collected from two studies: an open-label active aiTBS study for MDD and a double-blind, randomized control ...

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