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Effects of polygenic liability for autism on neonatal thalamocortical connectivity and behavioral outcomes across sex
2025-12-27
genetic and genomic medicine
Title + abstract only
View on medRxiv
Show abstract
Functional brain networks are altered in Autism Spectrum Disorder (ASD), with differences in thalamocortical connectivity detectable as early as infancy. ASD shows distinct sex differences, not only in diagnostic rates, but also in brain and behavioral manifestations of the condition. Although common variants account for much of the genetic liability for ASD, little is known about the impact of ASD-associated genetic variation on functional brain connectivity and behavioral outcomes in early lif...
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