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From Preservation to Regeneration: Stem Cell-Derived Therapies in Machine-Perfused Kidney Transplants : A systematic Review and Meta-analysis

2025-12-23 transplantation Title + abstract only
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The integration of regenerative medicine into dynamic organ preservation may mitigate ischemia-reperfusion injury in kidney transplantation. This systematic review and meta-analysis evaluated the therapeutic potential of stem cell-based interventions during machine perfusion. Following PRISMA guidelines, PubMed, Embase, and Scopus were searched for experimental studies using stem cells or extracellular vesicles (EVs) during hypothermic or normothermic machine perfusion in animal or discarded hum...

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