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Effect and Mechanisms of a Voice-based Coach using AI on Psychological Distress: A Phase 2 Randomized Trial
2025-12-29
psychiatry and clinical psychology
Title + abstract only
View on medRxiv
Show abstract
ImportanceArtificial Intelligence (AI) voice applications have the potential to address the unmet treatment needs among patients with depression and anxiety, but their therapeutic utility is largely unknown. ObjectiveTo investigate the efficacy and mechanisms of an AI-driven voice-based coach, Lumen, delivering problem-solving treatment (PST) for patients with untreated, moderate depression and/or anxiety. DesignPhase 2, 3-arm randomized clinical trial. SettingA public university and affiliat...
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