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Multivariate genome-wide association study of suicidal behaviors in >1.7 million individuals of diverse population descents

2025-12-16 genetic and genomic medicine Title + abstract only
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BackgroundWhile previous genome-wide association studies (GWAS) identified multiple risk loci for suicide ideation (SI) and suicide attempt (SA), there is still a limited understanding of the genetic predisposition underlying suicidal behaviors in diverse populations. This study aimed to conduct a large-scale investigation of the suicidality spectrum (SP) to generate new insights into its biology and epidemiology. MethodsLeveraging ancestrally diverse participants (SI Ncase/control=179 881/1 01...

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